This past week, we were able to visit the lab of Dr. Erin Calipari and Dr. James Crowe. Our first stop was in the laboratory of Dr. Calipari, and we were led by two postdoctoral fellows in her lab, Dr. Lillian Brandy and Dr. Alberto Lopez.
Dr. Brandy obtained her Ph.D. from the University of Alabama at Birmingham (UAB) in the Department of Neurobiology. While at UAB, Dr. Brandy worked with Dr. Lynn Dobrunz, where she studied the role of the dopamine system in the modulation and regulation of inhibitory synaptic transmission and neural circuit function within the hippocampus. Dr. Lopez graduated from Duke University in 2011 with a B.S. in Neuroscience. He worked for two years under Dr. Thomas Kash at UNC-Chapel Hill studying the neural mechanisms behind anxiety and alcoholism and then pursued a graduate degree at UC Irvine in 2013 with Dr. Wood. Within the Calipari lab, as a group are defining the neural dysfunction that underlies psychiatric disease. In particular, they are interested in answering two questions: how do neural circuits integrate experiences with positive and negative stimuli to guide future behavior, and what are the molecular dysregulations that drive maladaptation in these processes?
While touring their laboratory, they showed us the many visual approaches they use to carry out their work. One was a viral transfection technique, and the other was voltammetry. On the Calipari website, they briefly describe both of these techniques (pathway-specific rabies tracing and fast-scan cyclic voltammetry) along with some other techniques they use in the lab. For more information, comment below or email Dr. Brandy or Dr. Lopez at firstname.lastname@example.org or email@example.com, respectively.
Next, we visited the laboratory of Dr. James Crowe who, as we saw, uses a vast array of techniques, including molecular and cellular biology, state-of-the-art imaging, and flow cytometry, bioinformatics, and bioengineering approaches to study major human pathogens. Dr. Robert Carnahan and Ryan Irving led us through the incredible facilities that make up the Crowe laboratory, which includes over 45 members. Part of the group’s scientific philosophy is using study model systems only when the direct study of the primary pathogen in humans is not feasible. The current research in the Crowe lab includes respiratory syncytial virus, human metapneumovirus, rotavirus, HIV, influenza, and vaccinia virus.
After speaking with Dr. Cinque Soto, it is clear that visuals are needed for external and internal communication of scientific findings. From the recent call for cover art, Eve Moll, a junior here at Vanderbilt, prepared the image below and created the following description of her work. This is a great example of the final projects you are creating. The image is aesthetically attractive, and the message is clearly articulated and carefully created through the written description of the process. In many cases, the written description adds the most value and context on the impact of the work.
Here is another example that I put together with a description: